Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model

Shiga Toxin (Stx) Type 1a and Stx2a Translocate through a Three-Layer Intestinal Model

Shiga toxins (Stxs) produced by ingested <i>E. coli</i> can induce hemolytic uremic syndrome after crossing the intact intestinal barrier, entering the bloodstream, and targeting endothelial cells in the kidney. The method(s) by which the toxins reach the bloodstream are not fully define...

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Bibliographic Details
Main Authors: Rebecca A. Bova, Andrew C. Lamont, Theodore J. Picou, Vincent B. Ho, Kristin H. Gilchrist, Angela R. Melton-Celsa
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Toxins
Subjects:
tissue model
translocation
Shiga toxin
<i>Escherichia coli</i>
Online Access:https://www.mdpi.com/2072-6651/15/3/207

Internet

https://www.mdpi.com/2072-6651/15/3/207

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