A SNaPshot Assay for Determination of the Mannose-Binding Lectin Gene Variants and an Algorithm for Calculation of Haplogenotype Combinations

A SNaPshot Assay for Determination of the Mannose-Binding Lectin Gene Variants and an Algorithm for Calculation of Haplogenotype Combinations

Mannose-binding lectin (MBL) deficiency caused by the variability in the <i>MBL2</i> gene is responsible for the susceptibility to and severity of various infectious and autoimmune diseases. A combination of six single nucleotide polymorphisms (SNPs) has a major impact on MBL levels in c...

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Bibliographic Details
Main Authors: Jana Mrazkova, Petr Sistek, Jan Lochman, Lydie Izakovicova Holla, Zdenek Danek, Petra Borilova Linhartova
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Diagnostics
Subjects:
mannose-binding lectin
mannose-binding lectin gene (<i>MBL2</i>)
SNaPshot assay
single nucleotide polymorphism
genotyping
Haplogenotype Calculator
Online Access:https://www.mdpi.com/2075-4418/11/2/301

Internet

https://www.mdpi.com/2075-4418/11/2/301

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