Mutation of FLNA attenuating the migration of abdominal muscles contributed to Melnick–Needles syndrome (MNS) in a family with recurrent miscarriage

Mutation of FLNA attenuating the migration of abdominal muscles contributed to Melnick–Needles syndrome (MNS) in a family with recurrent miscarriage

Abstract Background Filamin A, encoded by the X‐linked gene FLNA, links the cell membrane with the cytoskeleton and acts as a regulator of the actin cytoskeleton. Mutations in FLNA cause a large spectrum of congenital malformations during embryonic development, including Melnick–Needles syndrome (MN...

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Bibliographic Details
Main Authors: Xin Luo, Zailin Yang, Jing Zeng, Jing Chen, Ningxuan Chen, Xiaoyan Jiang, Qinlv Wei, Ping Yi, Jing Xu
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
FLNA
Melnick–Needles syndrome
midline structure dysplasia
recurrent miscarriage
Online Access:https://doi.org/10.1002/mgg3.2145

Internet

https://doi.org/10.1002/mgg3.2145

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