Combined comparative genomics and clinical modeling reveals plasmid-encoded genes are independently associated with Klebsiella infection

Combined comparative genomics and clinical modeling reveals plasmid-encoded genes are independently associated with Klebsiella infection

Patient variables, such as comorbidities, partially explain which patients will progress to Klebsiella infection, with colonization of the gut acting as a reservoir. Little is known, however, regarding Klebsiella genes that may increase risk of disease in colonized individuals. Here, authors conduct...

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Bibliographic Details
Main Authors: Jay Vornhagen, Emily K. Roberts, Lavinia Unverdorben, Sophia Mason, Alieysa Patel, Ryan Crawford, Caitlyn L. Holmes, Yuang Sun, Alexandra Teodorescu, Evan S. Snitkin, Lili Zhao, Patricia J. Simner, Pranita D. Tamma, Krishna Rao, Keith S. Kaye, Michael A. Bachman
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31990-1

Internet

https://doi.org/10.1038/s41467-022-31990-1

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