A therapeutic vaccine strategy to prevent Pneumocystis pneumonia in an immunocompromised host in a non-human primate model of HIV and Pneumocystis co-infection

A therapeutic vaccine strategy to prevent Pneumocystis pneumonia in an immunocompromised host in a non-human primate model of HIV and Pneumocystis co-infection

IntroductionPneumocystis is a ubiquitous fungal pathogen that causes pneumonia (PCP) and pulmonary sequelae in HIV-infected individuals and other immunocompromised populations. With the success of anti-retroviral therapy for HIV-infected individuals the frequency of PCP in that population has decrea...

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Bibliographic Details
Main Authors: Whitney Rabacal, Finja Schweitzer, Heather M. Kling, Lizabeth Buzzelli, Emily Rayens, Karen A. Norris
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
Pneumocystis
Pneumocystis pneumonia (PCP/PJP)
fungal vaccine
α-galactosylceramide (α-GC, α-GalCer, KRN7000)
HIV/SIV
immunocompromised
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036658/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036658/full

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