The Effect of Conjugation of Ciprofloxacin and Moxifloxacin with Fatty Acids on Their Antibacterial and Anticancer Activity

The Effect of Conjugation of Ciprofloxacin and Moxifloxacin with Fatty Acids on Their Antibacterial and Anticancer Activity

Novel conjugates (CP) of moxifloxacin (MXF) with fatty acids (<b>1m</b>–<b>16m</b>) were synthesized with good yields utilizing amides chemistry. They exhibit a more pronounced cytotoxic potential than the parent drug. They were the most effective for prostate cancer cells wi...

Full description

Bibliographic Details
Main Authors: Alicja Chrzanowska, Marta Struga, Piotr Roszkowski, Michał Koliński, Sebastian Kmiecik, Karolina Jałbrzykowska, Anna Zabost, Joanna Stefańska, Ewa Augustynowicz-Kopeć, Małgorzata Wrzosek, Anna Bielenica
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
fluoroquinolone
conjugation
fatty acids
cytotoxicity
antibacterial activity
Online Access:https://www.mdpi.com/1422-0067/23/11/6261

Internet

https://www.mdpi.com/1422-0067/23/11/6261

Similar Items