Metabolic Alterations in Spheroid-Cultured Hepatic Stellate Cells

Metabolic Alterations in Spheroid-Cultured Hepatic Stellate Cells

Hepatic stellate cells (HSCs) play a vital role in liver fibrosis, and a greater understanding of their regulation is required. Recent studies have focused on relationships between extracellular matrix (ECM) stiffness and gene expression or cellular metabolism, but none have provided a detailed meta...

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Bibliographic Details
Main Authors: Koichi Fujisawa, Taro Takami, Nanami Sasai, Toshihiko Matsumoto, Naoki Yamamoto, Isao Sakaida
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:International Journal of Molecular Sciences
Subjects:
hepatic stellate cell
microgravity
transcriptome
spheroid
metabolome
αSMA
Online Access:https://www.mdpi.com/1422-0067/21/10/3451

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https://www.mdpi.com/1422-0067/21/10/3451

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