Creatine Supplementation Upregulates mTORC1 Signaling and Markers of Synaptic Plasticity in the Dentate Gyrus While Ameliorating LPS-Induced Cognitive Impairment in Female Rats

Creatine Supplementation Upregulates mTORC1 Signaling and Markers of Synaptic Plasticity in the Dentate Gyrus While Ameliorating LPS-Induced Cognitive Impairment in Female Rats

Mild cognitive impairment (MCI) designates the boundary area between cognitive function in natural aging and dementia, and this is viewed as a therapeutic window to prevent the occurrence of dementia. The current study investigated the neurocognitive effects of oral creatine (Cr) supplementation in...

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Bibliographic Details
Main Authors: Xuansong Mao, Taylor J. Kelty, Nathan R. Kerr, Thomas E. Childs, Michael D. Roberts, Frank W. Booth
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Nutrients
Subjects:
creatine
mild cognitive impairment
mTORC1
dentate gyrus
Online Access:https://www.mdpi.com/2072-6643/13/8/2758

Internet

https://www.mdpi.com/2072-6643/13/8/2758

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