High-Dimensional Analysis of Immune Cell Composition Predicts Periprosthetic Joint Infections and Dissects Its Pathophysiology

High-Dimensional Analysis of Immune Cell Composition Predicts Periprosthetic Joint Infections and Dissects Its Pathophysiology

Accurate diagnosis of periprosthetic joint infections (PJI) is one of the most widely researched areas in modern orthopedic endoprosthesis. However, our understanding of the immunological basis of this severe complication is still limited. In this study, we developed a flow cytometric approach to pr...

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Bibliographic Details
Main Authors: Maximilian F. Korn, Richard R. Stein, Andreas Dolf, Farhad Shakeri, Andreas Buness, Cäcilia Hilgers, Werner Masson, Sascha Gravius, Hendrik Kohlhof, Christof Burger, Dieter C. Wirtz, Thomas M. Randau, Frank A. Schildberg
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
periprosthetic joint synovial fluid
periprosthetic joint infection
aseptic implant failure
immune cell infiltrate
myeloid-derived suppressor cells
Online Access:https://www.mdpi.com/2227-9059/8/9/358

Internet

https://www.mdpi.com/2227-9059/8/9/358

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