CD24-Fc suppression of immune related adverse events in a therapeutic cancer vaccine model of murine neuroblastoma

CD24-Fc suppression of immune related adverse events in a therapeutic cancer vaccine model of murine neuroblastoma

IntroductionThe combination of Myc-suppressed whole tumor cells with checkpoint inhibitors targeting CTLA-4 and PD-L1 generates a potent therapeutic cancer vaccine in a mouse neuroblastoma model. As immunotherapies translate from pre-clinical to clinical trials, the potential immune-related adverse...

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Bibliographic Details
Main Authors: Xiaofang Wu, Priya Srinivasan, Mousumi Basu, Talia Zimmerman, Samuel Li, Yin Wang, Pan Zheng, Yang Liu, Anthony David Sandler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
CD24Fc
tumor cell vaccine
neuroblastoma
immune-related adverse events
autoimmune profiling
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1176370/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1176370/full

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