Glioblastoma CD105+ cells define a SOX2− cancer stem cell-like subpopulation in the pre-invasive niche

Glioblastoma CD105+ cells define a SOX2− cancer stem cell-like subpopulation in the pre-invasive niche

Abstract Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth, recurrence and patient prognosis. However, a better definition of GSC subpopulat...

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Bibliographic Details
Main Authors: Jiaxin Li, Fredrik Ek, Roger Olsson, Mattias Belting, Johan Bengzon
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Acta Neuropathologica Communications
Subjects:
CD105
Glioma stem-like cell
Exome sequencing
Drug screening
Tumor microenvironment
Online Access:https://doi.org/10.1186/s40478-022-01422-8

Internet

https://doi.org/10.1186/s40478-022-01422-8

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