Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1

Molecular basis for DNA recognition by the maternal pioneer transcription factor FoxH1

FoxH1 is an essential maternal pioneer factor during embryonic development. Here, the authors present several FoxH1—DNA structures that reveal the molecular basis for FoxH1 binding specificity and pioneer factor activity.

Bibliographic Details
Main Authors: Radoslaw Pluta, Eric Aragón, Nicholas A. Prescott, Lidia Ruiz, Rebeca A. Mees, Blazej Baginski, Julia R. Flood, Pau Martin-Malpartida, Joan Massagué, Yael David, Maria J. Macias
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34925-y

Internet

https://doi.org/10.1038/s41467-022-34925-y

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