Drosophila <i>O</i>-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes

Drosophila <i>O</i>-GlcNAcase Mutants Reveal an Expanded Glycoproteome and Novel Growth and Longevity Phenotypes

The reversible posttranslational <i>O</i>-GlcNAc modification of serine or threonine residues of intracellular proteins is involved in many cellular events from signaling cascades to epigenetic and transcriptional regulation. <i>O</i>-GlcNAcylation is a conserved nutrient-dep...

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Bibliographic Details
Main Authors: Ilhan Akan, Adnan Halim, Sergey Y. Vakhrushev, Henrik Clausen, John A. Hanover
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cells
Subjects:
<i>O</i>-GlcNAc proteome
growth
short life span
HCF
KISMET
SIN3A
Online Access:https://www.mdpi.com/2073-4409/10/5/1026

Internet

https://www.mdpi.com/2073-4409/10/5/1026

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