Prognostic Value of Circulating IGFBP2 and Related Autoantibodies in Children with Metastatic Rhabdomyosarcomas

Prognostic Value of Circulating IGFBP2 and Related Autoantibodies in Children with Metastatic Rhabdomyosarcomas

Insulin-like growth factor-binding protein 2 (IGFBP2) is a tumor-associated protein measurable in patients’ biopsies and blood samples. Increased IGFBP2 expression correlates with tumor severity in rhabdomyosarcoma (RMS). Thus, we examined the plasmatic IGFBP2 levels in 114 RMS patients an...

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Bibliographic Details
Main Authors: Elena Poli, Angelica Zin, Manuela Cattelan, Lucia Tombolan, Ilaria Zanetti, Angela Scagnellato, Paolo Bonvini, Gianni Bisogno
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Diagnostics
Subjects:
rhabdomyosarcoma
pediatric soft tissue sarcomas
plasmatic biomarkers
diagnostic and prognostic factors
tumor-associated antigens
tumor-associated autoantibodies
metastatic tumors
igfbp2
Online Access:https://www.mdpi.com/2075-4418/10/2/115

Internet

https://www.mdpi.com/2075-4418/10/2/115

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