Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity

In this study, two strains of the yeast <i>P. pastoris</i> were constructed, one of which produced authentic recombinant human granulocyte-macrophage colony-stimulating factor (ryGM-CSF), and the other was a chimera consisting of ryGM-CSF genetically fused with mature human apolipoprotei...

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Bibliographic Details
Main Authors: Mariya Pykhtina, Svetlana Miroshnichenko, Vladimir Romanov, Antonina Grazhdantseva, Galina Kochneva, Anatoly Beklemishev
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/5/459