Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid Model of Cartilage

Functionalized Nanogels with Endothelin-1 and Bradykinin Receptor Antagonist Peptides Decrease Inflammatory and Cartilage Degradation Markers of Osteoarthritis in a Horse Organoid Model of Cartilage

Osteoarthritis (OA) is a degenerative and heterogeneous disease that affects all types of joint structures. Current clinical treatments are only symptomatic and do not manage the degenerative process in animals or humans. One of the new orthobiological treatment strategies being developed to treat O...

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Bibliographic Details
Main Authors: Aurélie Cullier, Frédéric Cassé, Seng Manivong, Romain Contentin, Florence Legendre, Aracéli Garcia Ac, Pierre Sirois, Gaëlle Roullin, Xavier Banquy, Florina Moldovan, Lélia Bertoni, Fabrice Audigié, Philippe Galéra, Magali Demoor
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
chondrocyte
equine model
drug delivery system
bradykinin
endothelin-1
chitosan
Online Access:https://www.mdpi.com/1422-0067/23/16/8949

Internet

https://www.mdpi.com/1422-0067/23/16/8949

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