Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway

Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway

Abstract Receptor interacting serine/threonine protein kinase 1 (RIPK1) activation and necroptosis have been genetically and mechanistically linked with human multiple sclerosis and neurodegenerative diseases for which demyelination is a common key pathology. Demyelination can be healed through remy...

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Bibliographic Details
Main Authors: Xiao-Ru Ma, Shu-Ying Yang, Shuang-Shuang Zheng, Huan-Huan Yan, Hui-Min Gu, Fan Wang, Yang Wu, Zhao-Jun Dong, Di-Xian Wang, Yue Wang, Xianhui Meng, Jie Sun, Hong-Guang Xia, Jing-Wei Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00929-2

Internet

https://doi.org/10.1038/s41420-022-00929-2

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