Sustained release gel (polymer-free) of itraconazole-loaded microemulsion for oral candidiasis treatment: time-kill kinetics and cellular uptake

Sustained release gel (polymer-free) of itraconazole-loaded microemulsion for oral candidiasis treatment: time-kill kinetics and cellular uptake

AbstractItraconazole (ICZ) was prepared in a self-microemulsifying (SM) gel. This gel was intended for use in the oral mucosa, where low volume and flow of saliva result in limited solubility and absorption of drugs that are poorly water-soluble. The drug-loaded gel formulation (ICZ-SM) was selected...

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Bibliographic Details
Main Authors: Sukannika Tubtimsri, Yotsanan Weerapol
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Drug Delivery
Subjects:
Itraconazole
self-microemulsion
oral mucosa gel
oral candidiasis
time-kill kinetics
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2023.2234099

Internet

https://www.tandfonline.com/doi/10.1080/10717544.2023.2234099

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