IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

IgG Binds Escherichia coli Serine Protease EspP and Protects Mice From E. coli O157:H7 Infection

Shiga toxin-producing Escherichia coli O157:H7 is a virulent strain causing severe gastrointestinal infection, hemolytic uremic syndrome and death. To date there are no specific therapies to reduce progression of disease. Here we investigated the effect of pooled immunoglobulins (IgG) on the course...

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Bibliographic Details
Main Authors: Ashmita Tontanahal, Vanessa Sperandio, Olga Kovbasnjuk, Sebastian Loos, Ann-Charlotte Kristoffersson, Diana Karpman, Ida Arvidsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
Escherichia coli O157:H7
Shiga toxin
EspP
immunoglobulin G
hemolytic uremic syndrome
mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.807959/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.807959/full

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