An Integrative Transcriptome-Wide Analysis of Amyotrophic Lateral Sclerosis for the Identification of Potential Genetic Markers and Drug Candidates

An Integrative Transcriptome-Wide Analysis of Amyotrophic Lateral Sclerosis for the Identification of Potential Genetic Markers and Drug Candidates

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative neuromuscular disease. Although genome-wide association studies (GWAS) have successfully identified many variants significantly associated with ALS, it is still difficult to characterize the underlying biological mechanisms inducing ALS. In...

Full description

Bibliographic Details
Main Authors: Sungmin Park, Daeun Kim, Jaeseung Song, Jong Wha J. Joo
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
amyotrophic lateral sclerosis
transcriptome-wide association study
drug repositioning
enrichment analysis
causal gene
Online Access:https://www.mdpi.com/1422-0067/22/6/3216

Internet

https://www.mdpi.com/1422-0067/22/6/3216

Similar Items