Cooperative regulation of Zhx1 and hnRNPA1 drives the cardiac progenitor-specific transcriptional activation during cardiomyocyte differentiation

Abstract The zinc finger proteins (ZNFs) mediated transcriptional regulation is critical for cell fate transition. However, it is still unclear how the ZNFs realize their specific regulatory roles in the stage-specific determination of cardiomyocyte differentiation. Here, we reported that the zinc f...

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Bibliographic Details
Main Authors: Yang Chen, Yukang Wu, Jianguo Li, Kai Chen, Wuchan Wang, Zihui Ye, Ke Feng, Yiwei Yang, Yanxin Xu, Jiuhong Kang, Xudong Guo
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01548-1