Detection of Heteromers Formed by Cannabinoid CB1, Dopamine D2, and Adenosine A2A G-Protein-Coupled Receptors by Combining Bimolecular Fluorescence Complementation and Bioluminescence Energy Transfer

Detection of Heteromers Formed by Cannabinoid CB1, Dopamine D2, and Adenosine A2A G-Protein-Coupled Receptors by Combining Bimolecular Fluorescence Complementation and Bioluminescence Energy Transfer

Functional interactions in signaling occur between dopamine D2 (D2R) and cannabinoid CB1 (CB1R) receptors, between CB1R and adenosine A2A (A2AR) receptors, and between D2R and A2AR. Furthermore, direct molecular interactions have been reported for the pairs CB1R-D2R, A2AR-D2R, and CB1R-A2AR. Here a...

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Bibliographic Details
Main Authors: Gemma Navarro, Paulina Carriba, Jorge Gandí, Francisco Ciruela, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carmen Lluis, Rafael Franco
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2008.136

Internet

http://dx.doi.org/10.1100/tsw.2008.136

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