Mechanically strained osteocyte-derived exosomes contained miR-3110-5p and miR-3058-3p and promoted osteoblastic differentiation

Abstract Background Osteocytes are critical mechanosensory cells in bone, and mechanically stimulated osteocytes produce exosomes that can induce osteogenesis. MicroRNAs (miRNAs) are important constituents of exosomes, and some miRNAs in osteocytes regulate osteogenic differentiation; previous studi...

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Bibliographische Detailangaben
Hauptverfasser: Yingwen Zhu, Yanan Li, Zhen Cao, Jindong Xue, Xiaoyan Wang, Tingting Hu, Biao Han, Yong Guo
Format: Artikel
Sprache:English
Veröffentlicht: BMC 2024-05-01
Schriftenreihe:BioMedical Engineering OnLine
Schlagworte:
Online Zugang:https://doi.org/10.1186/s12938-024-01237-9