High expression of HuR in cytoplasm, but not nuclei, is associated with malignant aggressiveness and prognosis in bladder cancer.

INTRODUCTION: Human antigen R (HuR) regulates the stability of mRNA and is associated with cell proliferation, angiogenesis, and lymphangiogenesis. However, the clinical significance and pathological role of HuR in bladder cancer remains unclear. The main objective of this investigation was to clari...

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Bibliographic Details
Main Authors: Yasuyoshi Miyata, Shin-ichi Watanabe, Yuji Sagara, Kensuke Mitsunari, Tomohiro Matsuo, Kojiro Ohba, Hideki Sakai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3596286?pdf=render