Increased Risk for Atrial Alternans in Rabbit Heart Failure: The Role of Ca<sup>2+</sup>/Calmodulin-Dependent Kinase II and Inositol-1,4,5-trisphosphate Signaling

Increased Risk for Atrial Alternans in Rabbit Heart Failure: The Role of Ca<sup>2+</sup>/Calmodulin-Dependent Kinase II and Inositol-1,4,5-trisphosphate Signaling

Heart failure (HF) increases the probability of cardiac arrhythmias, including atrial fibrillation (AF), but the mechanisms linking HF to AF are poorly understood. We investigated disturbances in Ca<sup>2+</sup> signaling and electrophysiology in rabbit atrial myocytes from normal and fa...

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Bibliographic Details
Main Authors: Giedrius Kanaporis, Lothar A. Blatter
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomolecules
Subjects:
heart failure
atria
alternans
calcium
Ca<sup>2+</sup>/calmodulin-dependent kinase II
arrhythmia
Online Access:https://www.mdpi.com/2218-273X/14/1/53

Internet

https://www.mdpi.com/2218-273X/14/1/53

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