Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling

Proximity proteomics reveals role of Abelson interactor 1 in the regulation of TAK1/RIPK1 signaling

Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity‐dependent labeling (PDL) with biotin followed by mass spectrometry. Using a novel PDL data fil...

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Bibliographic Details
Main Authors: Max Petersen, Anna Chorzalska, Makayla Pardo, Anaelena Rodriguez, John Morgan, Nagib Ahsan, Ting C. Zhao, Olin Liang, Leszek Kotula, Paul Bertone, Philip A. Gruppuso, Patrycja M. Dubielecka
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Molecular Oncology
Subjects:
ABL interactor 1
NF‐κB
proximity proteomics
RIPK1
TAK1
TurboID
Online Access:https://doi.org/10.1002/1878-0261.13374

Internet

https://doi.org/10.1002/1878-0261.13374

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