Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

Abstract During the establishment of pregnancy, extravillous trophoblast (EVT) must invade into the uterine decidua to facilitate decidual artery remodelling to create the placental blood supply. The local decidual environment is thought to regulate trophoblast invasion, however these interactions a...

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Bibliographic Details
Main Authors: E. M. Menkhorst, M. L. Van Sinderen, K. Rainczuk, C. Cuman, A. Winship, E. Dimitriadis
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05947-0