Genetic Ablation of a Female-Specific Apetala 2 Transcription Factor Blocks Oocyst Shedding in Cryptosporidium parvum

Genetic Ablation of a Female-Specific Apetala 2 Transcription Factor Blocks Oocyst Shedding in Cryptosporidium parvum

ABSTRACT The apicomplexan parasite Cryptosporidium is a leading global cause of diarrheal disease, and the infection poses a particularly grave threat to young children and those with weakened immune function. Infection occurs by ingestion of meiotic spores called oocysts, and transmission relies on...

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Bibliographic Details
Main Authors: Jayesh Tandel, Katelyn A. Walzer, Jessica H. Byerly, Brittain Pinkston, Daniel P. Beiting, Boris Striepen
Format: Article
Language:English
Published: American Society for Microbiology 2023-04-01
Series:mBio
Subjects:
AP2
Cryptosporidium
apicomplexan parasites
intestine
sex
transcription
Online Access:https://journals.asm.org/doi/10.1128/mbio.03261-22

Internet

https://journals.asm.org/doi/10.1128/mbio.03261-22

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