Common Transcriptional Program of Liver Fibrosis in Mouse Genetic Models and Humans

Common Transcriptional Program of Liver Fibrosis in Mouse Genetic Models and Humans

Multifactorial metabolic diseases, such as non-alcoholic fatty liver disease, are a major burden to modern societies, and frequently present with no clearly defined molecular biomarkers. Herein we used system medicine approaches to decipher signatures of liver fibrosis in mouse models with malfuncti...

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Bibliographic Details
Main Authors: Kaja Blagotinšek Cokan, Žiga Urlep, Miha Moškon, Miha Mraz, Xiang Yi Kong, Winnie Eskild, Damjana Rozman, Peter Juvan, Tadeja Režen
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
NAFLD
NASH
bile acid
GEM
fibrosis
fatty acid
Online Access:https://www.mdpi.com/1422-0067/22/2/832

Internet

https://www.mdpi.com/1422-0067/22/2/832

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