Modulation of Endolysin LysECD7 Bactericidal Activity by Different Peptide Tag Fusion

Modulation of Endolysin LysECD7 Bactericidal Activity by Different Peptide Tag Fusion

The use of recombinant endolysins is a promising approach for antimicrobial therapy capable of counteracting the spread of antibiotic-resistant strains. To obtain the necessary biotechnological product, diverse peptide tags are often fused to the endolysin sequence to simplify enzyme purification, i...

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Bibliographic Details
Main Authors: Nataliia P. Antonova, Daria V. Vasina, Evgeny O. Rubalsky, Mikhail V. Fursov, Alina S. Savinova, Igor V. Grigoriev, Evgeny V. Usachev, Natalia V. Shevlyagina, Vladimir G. Zhukhovitsky, Vadim U. Balabanyan, Vasiliy D. Potapov, Andrey V. Aleshkin, Valentine V. Makarov, Sergey M. Yudin, Alexander L. Gintsburg, Artem P. Tkachuk, Vladimir A. Gushchin
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Biomolecules
Subjects:
endolysin
peptide tags
bactericidal activity
enzyme properties
eskape pathogens
Online Access:https://www.mdpi.com/2218-273X/10/3/440

Internet

https://www.mdpi.com/2218-273X/10/3/440

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