Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses

Crystal Structures of Inhibitor-Bound Main Protease from Delta- and Gamma-Coronaviruses

With the spread of SARS-CoV-2 throughout the globe causing the COVID-19 pandemic, the threat of zoonotic transmissions of coronaviruses (CoV) has become even more evident. As human infections have been caused by alpha- and beta-CoVs, structural characterization and inhibitor design mostly focused on...

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Bibliographic Details
Main Authors: Sarah N. Zvornicanin, Ala M. Shaqra, Qiuyu J. Huang, Elizabeth Ornelas, Mallika Moghe, Mark Knapp, Stephanie Moquin, Dustin Dovala, Celia A. Schiffer, Nese Kurt Yilmaz
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
coronaviruses
main protease
GC376
crystal structure
lufotrelvir
HKU15
Online Access:https://www.mdpi.com/1999-4915/15/3/781

Internet

https://www.mdpi.com/1999-4915/15/3/781

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