Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection

Commensal bacteria within the gut microbiome contribute to development of host tolerance to infection, however, identifying specific microbes responsible for this response is difficult. Here we describe methods for developing microfluidic organ-on-a-chip models of small and large intestine lined wit...

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Bibliographic Details
Main Authors: Francesca S. Gazzaniga, Diogo M. Camacho, Meng Wu, Matheus F. Silva Palazzo, Alexandre L. M. Dinis, Francis N. Grafton, Mark J. Cartwright, Michael Super, Dennis L. Kasper, Donald E. Ingber
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.638014/full