Association between urinary uric acid excretion and kidney outcome in patients with CKD

Abstract Inhibiting tubular urate reabsorption may protect the kidney from urate-induced tubular injury. However, this approach may promote intratubular uric acid crystallization, especially in acidified urine, which could be toxic to the kidney. To assess how tubular urate handling affects kidney o...

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Bibliographic Details
Main Authors: Yuta Asahina, Yusuke Sakaguchi, Tatsufumi Oka, Koki Hattori, Takayuki Kawaoka, Yohei Doi, Ryohei Yamamoto, Isao Matsui, Masayuki Mizui, Jun-Ya Kaimori, Yoshitaka Isaka
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-55809-9