Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis
Abstract Background Increased oxidative stress contributes to enhanced osteoclastogenesis and age-related bone loss. Melatonin (MT) is an endogenous antioxidant and declines with aging. However, it was unclear whether the decline of MT was involved in the enhanced osteoclastogenesis during the aging...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s10020-024-00779-x |