Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes

Summary: The small 3-O-sulfated galactose head group of sulfatides, an abundant glycosphingolipid class, poses the (sphinx-like) riddle on involvement of glycan bridging by tissue lectins (sugar code). First, synthesis of head group derivatives for functionalization of amphiphilic dendrimers is perf...

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Bibliographic Details
Main Authors: Paul V. Murphy, Antonio Romero, Qi Xiao, Anna-Kristin Ludwig, Srinivas Jogula, Nadezhda V. Shilova, Tanuja Singh, Adele Gabba, Bilal Javed, Dapeng Zhang, Francisco J. Medrano, Herbert Kaltner, Jürgen Kopitz, Nicolai V. Bovin, Albert M. Wu, Michael L. Klein, Virgil Percec, Hans-Joachim Gabius
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220311160