Lymphatic blood filling in CLEC-2-deficient mouse models

Lymphatic blood filling in CLEC-2-deficient mouse models

C-type lectin-like receptor 2 (CLEC-2) is considered as a potential drug target in settings of wound healing, inflammation, and infection. A potential barrier to this is evidence that CLEC-2 and its ligand podoplanin play a critical role in preventing lymphatic vessel blood filling in mice throughou...

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Bibliographic Details
Main Authors: Elizabeth J Haining, Kate L Lowe, Surasak Wichaiyo, Raghu P Kataru, Zoltan Nagy, Dean Pj Kavanagh, Sian Lax, Ying Di, Bernhard Nieswandt, Benoît Ho-Tin-Noé, Babak J Mehrara, Yotis A Senis, Julie Rayes, Steve P Watson
Format: Article
Language:English
Published: Taylor & Francis Group 2021-04-01
Series:Platelets
Subjects:
blood-lymphatic separation
clec-2
platelets
podoplanin
Online Access:http://dx.doi.org/10.1080/09537104.2020.1734784

Internet

http://dx.doi.org/10.1080/09537104.2020.1734784

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