SeqClone: sequential Monte Carlo based inference of tumor subclones

SeqClone: sequential Monte Carlo based inference of tumor subclones

Abstract Background Tumor samples are heterogeneous. They consist of varying cell populations or subclones and each subclone is characterized with a distinct single nucleotide variant (SNV) profile. This explains the source of genetic heterogeneity observed in tumor sequencing data. To make precise...

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Detaylı Bibliyografya
Asıl Yazarlar: Oyetunji E. Ogundijo, Xiaodong Wang
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: BMC 2019-01-01
Seri Bilgileri:BMC Bioinformatics
Konular:
Tumor heterogeneity
Bayesian model
Sequential Monte Carlo
Indian buffet process
Online Erişim:http://link.springer.com/article/10.1186/s12859-018-2562-y

Internet

http://link.springer.com/article/10.1186/s12859-018-2562-y

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