Increased CD4+/CD8+ double-positive T cells in chronic Chagasic patients.

BACKGROUND: CD4+/CD8+ double positive (DP) T cells have been described in healthy individuals as well as in patients with autoimmune and chronic infectious diseases. In chronic viral infections, this cell subset has effector memory phenotype and displays antigen specificity. No previous studies of d...

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Bibliographic Details
Main Authors: Nicolas A Giraldo, Natalia I Bolaños, Adriana Cuellar, Fanny Guzman, Ana Maria Uribe, Astrid Bedoya, Natalia Olaya, Zulma M Cucunubá, Nubia Roa, Fernando Rosas, Víctor Velasco, Concepción J Puerta, John M González
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3160296?pdf=render