Optimized Methods for Analytical and Functional Comparison of Biosimilar mAb Drugs: A Case Study for Avastin, Mvasi, and Zirabev

Optimized Methods for Analytical and Functional Comparison of Biosimilar mAb Drugs: A Case Study for Avastin, Mvasi, and Zirabev

Bevacizumab is a humanized therapeutic monoclonal antibody used to reduce angiogenesis, a hallmark of cancer, by binding to VEGF-A. Many pharmaceutical companies have developed biosimilars of Bevacizumab in the last decade. The official reports provided by the FDA and EMA summarize the analytical pe...

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Bibliographic Details
Main Authors: Büşra Gürel, Eda Çapkın, Ayhan Parlar, Aylin Özkan, Meltem Çorbacıoğlu, Duygu Emine Dağlikoca, Meral Yüce
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Scientia Pharmaceutica
Subjects:
Bevacizumab
Mvasi
Zirabev
biosimilar drugs
analytical characterization
functional similarity
Online Access:https://www.mdpi.com/2218-0532/90/2/36

Internet

https://www.mdpi.com/2218-0532/90/2/36

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