VNAR development through antigen immunization of Japanese topeshark (Hemitriakis japanica)

VNAR development through antigen immunization of Japanese topeshark (Hemitriakis japanica)

The VNAR (Variable New Antigen Receptor) is the smallest single-domain antibody derived from the variable domain of IgNAR of cartilaginous fishes. Despite its biomedical and diagnostic potential, research on VNAR has been limited due to the difficulties in obtaining and maintaining immune animals an...

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Bibliographic Details
Main Authors: Hiroyuki Takeda, Tatsuhiko Ozawa, Hiroki Zenke, Yoh Ohnuki, Yuri Umeda, Wei Zhou, Honoka Tomoda, Akihiko Takechi, Kimiyoshi Narita, Takaaki Shimizu, Takuya Miyakawa, Yuji Ito, Tatsuya Sawasaki
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
VNAR
Japanese topeshark
phage display
yeast display
biopanning
deep sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1265582/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1265582/full

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