Weakly supervised deep learning to predict recurrence in low-grade endometrial cancer from multiplexed immunofluorescence images

Abstract Predicting recurrence in low-grade, early-stage endometrial cancer (EC) is both challenging and clinically relevant. We present a weakly-supervised deep learning framework, NaroNet, that can learn, without manual expert annotation, the complex tumor-immune interrelations at three levels: lo...

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Bibliographic Details
Main Authors: Daniel Jiménez-Sánchez, Álvaro López-Janeiro, María Villalba-Esparza, Mikel Ariz, Ece Kadioglu, Ivan Masetto, Virginie Goubert, Maria D. Lozano, Ignacio Melero, David Hardisson, Carlos Ortiz-de-Solórzano, Carlos E. de Andrea
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Digital Medicine
Online Access:https://doi.org/10.1038/s41746-023-00795-x