Lifelong exposure to n-3 PUFA deficiency leads to anxiety-like profile in male and female adolescent rats: Impact on spleen-brain axis

Low consumption of n-3 polyunsaturated fatty acids (PUFA) during the developmental period has been increasingly associated with an increased risk of depressive-like symptoms in both male and female sexes. Therefore, here we performed behavioral and biochemical quantifications in adolescent rats to e...

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Bibliographic Details
Main Authors: Maria Bove, Stefania Schiavone, Paolo Tucci, Lisa Pia Agosti, Stefania Dimonte, Maria Adelaide Palmieri, Vladyslav Sikora, Maria Matteo, Luigia Trabace, Maria Grazia Morgese
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223015780