A New Method for Next-Generation Sequencing of the Full Hepatitis B Virus Genome from A Clinical Specimen: Impact for Virus Genotyping

A New Method for Next-Generation Sequencing of the Full Hepatitis B Virus Genome from A Clinical Specimen: Impact for Virus Genotyping

Hepatitis B virus (HBV) is an enveloped virus that induces chronic liver disease. HBV has been classified into eight genotypes (A–H) according to its genome sequence by using Sanger sequencing or reverse hybridization. Sanger sequencing is often restricted to analyzing the S gene and is inaccurate f...

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Bibliographic Details
Main Authors: Flavia Hebeler-Barbosa, Ivan Rodrigo Wolf, Guilherme Targino Valente, Francisco Campello do Amaral Mello, Elisabeth Lampe, Maria Inês de Moura Campos Pardini, Rejane Maria Tommasini Grotto
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
Hepatitis B virus
NGS
genotyping
phylogeny analysis
Online Access:https://www.mdpi.com/2076-2607/8/9/1391

Internet

https://www.mdpi.com/2076-2607/8/9/1391

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