Seeding of proteins into amyloid structures by metabolite assemblies may clarify certain unexplained epidemiological associations

The accumulation of various metabolites appears to be associated with diverse human diseases. However, the aetiological link between metabolic alteration and the observed diseases is still elusive. This includes the correlation between the abnormally high levels of homocysteine and quinolinic acid i...

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Bibliographic Details
Main Authors: Dorin Sade, Shira Shaham-Niv, Zohar A. Arnon, Omid Tavassoly, Ehud Gazit
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170229