Effect of the antirheumatic medication methotrexate (MTX) on biomechanical compressed human periodontal ligament fibroblasts (hPDLFs)

Abstract Background The aim of this study was to investigate the in vitro effect of the antirheumatic drug methotrexate (MTX) on biomechanically compressed human periodontal ligament fibroblasts (hPDLFs), focusing on the expression of interleukin 6 (IL-6), as its upregulation is relevant to orthodon...

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Bibliographic Details
Main Authors: Claudia Welte-Jzyk, Vera Plümer, Sven Schumann, Andrea Pautz, Christina Erbe
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-024-04092-1