Gene expression profiles (GEPs) of immuno-oncologic pathways as predictors of response to checkpoint inhibitors in advanced NSCLC

Gene expression profiles (GEPs) of immuno-oncologic pathways as predictors of response to checkpoint inhibitors in advanced NSCLC

Background: Immune checkpoint inhibitors (ICIs) revolutionized non-small-cell lung cancer (NSCLC) treatment. However, improving patients’ selection for this therapy is needed. Gene expression profile (GEP) is a promising biomarker tool. We assessed the predictive value of 48 onco-immune GEPs in an N...

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Bibliographic Details
Main Authors: Pedro De Marchi, Leticia Ferro Leal, Luciane Sussuchi da Silva, Rodrigo de Oliveira Cavagna, Flavio Augusto Ferreira da Silva, Vinicius Duval da Silva, Eduardo CA da Silva, Augusto O. Saito, Vladmir C. Cordeiro de Lima, Rui Manuel Reis
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Translational Oncology
Subjects:
Non-small cell lung cancer
NSCLC
Immunotherapy
anti-PD-(L)1
anti-CTLA-4
PD-L1
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523323002048

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http://www.sciencedirect.com/science/article/pii/S1936523323002048

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