Overexpression of WRAP53 is associated with development and progression of esophageal squamous cell carcinoma.

BACKGROUND:Esophageal squamous cell carcinoma (ESCC) is a highly aggressive cancer whose underlying molecular mechanisms are poorly understood. The natural antisense transcript (NAT) WRAP53 regulates p53 expression and WRAP53 protein is a component of telomerase. NATs play key roles in carcinogenesi...

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Bibliographic Details
Main Authors: Xuguang Rao, Daofu Huang, Xuxia Sui, Gefei Liu, Xuhong Song, Jinglian Xie, Dongyang Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3953598?pdf=render