Vitamin D and prebiotics for intestinal health in cystic fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 x 2 trial of administration of prebiotics and cholecalciferol (vitamin D3) (Pre-D trial) in adults with cystic fibrosis

Vitamin D and prebiotics for intestinal health in cystic fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 x 2 trial of administration of prebiotics and cholecalciferol (vitamin D3) (Pre-D trial) in adults with cystic fibrosis

Individuals with cystic fibrosis (CF) have dysfunctional intestinal microbiota and increased gastrointestinal (GI) inflammation also known as GI dysbiosis. It is hypothesized that administration of high-dose cholecalciferol (vitamin D3) together with a prebiotic (inulin) will be effective, and possi...

Full description

Bibliographic Details
Main Authors: Alisa K. Sivapiromrat, Pichatorn Suppakitjanusant, Yanling Wang, Chengcheng Hu, Jose Binongo, William R. Hunt, Samuel Weinstein, Ishaan Jathal, Jessica A. Alvarez, Benoit Chassaing, Thomas R. Ziegler, Andrew T. Gewirtz, Vin Tangpricha
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865424000255

Internet

http://www.sciencedirect.com/science/article/pii/S2451865424000255

Similar Items