Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion

Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion

Abstract Background DNA methylation is a critical molecular mark involved in cellular differentiation and cell-specific processes. Single-cell whole genome DNA methylation profiling methods hold great potential to resolve the DNA methylation profiles of individual cell-types. Here we present a metho...

Full description

Bibliographic Details
Main Authors: Zac Chatterton, Praves Lamichhane, Diba Ahmadi Rastegar, Lauren Fitzpatrick, Hélène Lebhar, Christopher Marquis, Glenda Halliday, John B. Kwok
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell & Bioscience
Subjects:
Epigenetics
DNA methylation
Single-cell
Brain
APOBEC
Online Access:https://doi.org/10.1186/s13578-022-00938-9

Internet

https://doi.org/10.1186/s13578-022-00938-9

Similar Items