Analytical and Sample Preparation Protocol for Therapeutic Drug Monitoring of 12 Thiopurine Metabolites Related to Clinical Treatment of Inflammatory Bowel Disease

Analytical and Sample Preparation Protocol for Therapeutic Drug Monitoring of 12 Thiopurine Metabolites Related to Clinical Treatment of Inflammatory Bowel Disease

Thiopurines (TP) represent an important therapeutic tool for the treatment of inflammatory bowel diseases (IBD) in the current situation of rising incidence and health care costs. The results of multiple clinical studies aimed at finding correlations between levels of TP metabolites and response of...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Daniel Pecher, Svetlana Dokupilová, Zuzana Zelinková, Maikel Peppelenbosch, Jana Lučeničová, Veronika Mikušová, Peter Mikuš
स्वरूप: लेख
भाषा:English
प्रकाशित: MDPI AG 2018-07-01
श्रृंखला:Molecules
विषय:
inflammatory bowel diseases
therapeutic drug monitoring
profiling of thiopurines
comprehensive stability study
sample treatment
clinical analysis
high performance liquid chromatography
mass spectrometry
ऑनलाइन पहुंच:http://www.mdpi.com/1420-3049/23/7/1744

इंटरनेट

http://www.mdpi.com/1420-3049/23/7/1744

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